Drifters in search of work, George and his childlike friend Lennie, have nothing in the world except the clothes on their back - and a dream that one day they will have some land of their own. Eventually they find work on a ranch in California s Salinas Valley, but their hopes are dashed as Lennie - struggling against extreme cruelty, misunderstanding and feelings of jealousy - becomes a victim of his own strength. Tackling universal themes of friendship and shared vision, and giving a voice to America s lonely and dispossessed, Of Mice and Men remains Steinbeck s most popular work, achieving success as a novel, Broadway play and three acclaimed films.